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August 15, 2020
ATIM-14. Results of Phase II Clinical Trial of Oncolytic Herpes Virus G47∆ in Patients with Glioblastoma Bookmark
George Lundberg, MDResearch paper from Neuro-Oncology curated by Editor in Chief George Lundberg, MD, who notes:
In a phase 2 clinical trial, glioblastoma patients were treated with a herpes virus that has been genetically engineered to kill cancer cells. The genetically engineered virus is injected directly into patients’ brain tumors. It is early and the numbers are small, but the trial produced amazing results compared to historical controls.
Go to full paper published in Neuro-Oncology.
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August 15, 2020
Lung cancer at ASCO20 Virtual Bookmark
George Lundberg, MDResearch highlight from Nature Reviews Clinical Oncology curated by Editor in Chief George Lundberg, MD, who notes:
This year’s virtual meeting of the American Society of Clinical Oncology featured presentations on several different targeted therapies that appear to provide improved outcomes for lung cancer patients.
Go to full research highlight published by Nature Reviews Clinical Oncology.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
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August 15, 2020
ICI for Resected Stage IV Melanoma Bookmark
George Lundberg, MDResearch highlight from Nature Reviews Clinical Oncology curated by Editor in Chief George Lundberg, MD, who notes:
In a clinical trial for metastatic melanoma patients, a combination of the drugs nivolumab and ipilimumab (both “immune checkpoint inhibitors,” or ICIs) outperformed nivolumab on its own, and nivolumab on its own outperformed a placebo.
Go to full research highlight published by Nature Reviews Clinical Oncology.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
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August 15, 2020
Key Studies in Metastatic Breast Cancer From ASCO 2020 Bookmark
George Lundberg, MDArticle from Medscape curated by Editor in Chief George Lundberg, MD, who notes:
This year’s virtual meeting of the American Society of Clinical Oncology (ASCO) featured five important studies on metastatic breast cancer, as outlined in this video.
Go to full article and video published by Medscape.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
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August 14, 2020
Is Polio the Answer to Curing Brain Tumors? Bookmark
George Lundberg, MDArticle from WKYC Studios curated by Editor in Chief George Lundberg, MD, who notes:
An experimental treatment in which the virus that causes polio is directly injected into glioblastoma (GBM) tissue has shown some promise, as reported in the New England Journal of Medicine in 2018. This news story from WKYC provides a partial update from an ongoing subsequent clinical trial.
Go to full article published by WKYC Studios.
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August 14, 2020
A Phase II Randomized, Multicenter, Open-Label Trial of Continuing Adjuvant Temozolomide Beyond Six Cycles in Patients With Glioblastoma (GEINO 14-01) Bookmark
George Lundberg, MDResearch paper from Neuro-Oncology curated by Editor in Chief George Lundberg, MD, who notes:
These clinical trial results suggest that six cycles of temozolomide is as effective as 12 for patients with glioblastoma and produces fewer side effects.
Go to full paper published in Neuro-Oncology.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
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August 7, 2020
Final Results from KEYNOTE-100 Show Promise for Pembrolizumab Monotherapy Bookmark
George Lundberg, MDArticle from Cancer Network curated by Editor in Chief George Lundberg, MD, who notes:
Treatment with pembrolizumab (brand name Keytruda) on its own shows modest responses in patients with recurrent ovarian cancer.
Go to full article published by Cancer Network.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
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May 30, 2020
Atezolizumab Plus Bevacizumab vs Sorafenib in Treatment-Naive Patients With Unresectable Hepatocellular Carcinoma Bookmark
George Lundberg, MDArticle from The ASCO Post curated by Editor in Chief George Lundberg, MD, who notes:
In a clinical trial, a combination of the drugs atezolizumab and bevacizumab improved both progression-free survival and overall survival in advanced hepatocarcinoma (the most common form of liver cancer), with fewer adverse effects. These findings were reported in the New England Journal of Medicine.
Go to full article published by The ASCO Post.
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May 30, 2020
Randomized Phase II Trial of Nivolumab Versus Nivolumab and Ipilimumab for Recurrent or Persistent Ovarian Cancer: An NRG Oncology Study Bookmark
George Lundberg, MDResearch paper from the Journal of Clinical Oncology curated by Editor in Chief George Lundberg, MD, who notes:
Eighty percent of ovarian cancers are first diagnosed after they have already spread. In the clinical trial discussed in this paper, a combination of two checkpoint inhibitor immunotherapy drugs showed only modest benefit in advanced ovarian cancer.
Go to full paper published in the Journal of Clinical Oncology.
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January 6, 2020
Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer Bookmark
George Lundberg, MDResearch paper from The New England Journal of Medicine curated by Editor in Chief George Lundberg, MD, who notes:
These clinical trials results suggest that the drug niraparib is superior to platinum-based chemotherapy for people with newly diagnosed advanced ovarian cancer.
Go to full paper published in The New England Journal of Medicine.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
Clinical Trial Results
Some of the most promising new treatments for advanced cancer are currently being tested in patients enrolled in clinical trials. We help you stay up to date on the latest results from these studies.
