Olaparib Granted Positive EU Opinion for BRCA1/2+ Advanced Prostate Cancer Bookmark

A news story published by OncLive reports that the European Union’s Committee for Medicinal Products for Human Use recently approved the drug olaparib for treating patients with a subset of advanced castrate-resistant prostate cancers that have BRCA1/2 mutations.

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For Esophageal Cancer, Immunotherapy Likely to Play Larger Role Bookmark

A blog post from the National Cancer Institute reports that two clinical trials are showing encouraging results for progression-free survival—and one for overall survival—from treatment with immunotherapy drugs in people with advanced esophageal cancer. 

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Two New Treatments Approved For Advanced Prostate Cancer Bookmark

A story published by the Prostate Cancer Foundation outlines two new treatment options approved by the U.S. Food and Drug Administration (FDA) this year. The two medications, rucaparib and olaparib, each target specific mutations that may be found in a patient’s tumor, and each was approved for a specific type of prostate cancer.

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Cancer Vaccine UV1 Plus Keytruda Shows Safety, Early Efficacy in Advanced Melanoma Trial Bookmark

A story from Immuno-Oncology News covers new results from a phase 1 clinical trial that indicate promising safety and early efficacy of a treatment that combines the drug Keytruda and an experimental cancer vaccine for people with advanced melanoma.

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Efficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib Bookmark

This scientific research paper published in JAMA Oncology reports results from a clinical trial in which the drugs nivolumab and ipilimumab showed promising safety and efficacy for people with advanced liver cancer who had previously received the drug sorafenib.

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Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma Bookmark

This academic research paper from The New England Journal of Medicine reports results from a clinical trial in which a treatment that combines the drugs atezolizumab and bevacizumab improved both progression-free and overall survival for people with unresectable primary liver cancer.

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ESMO 2019: Immunotherapy in Cervical and Endometrial Cancers Bookmark

Article from The ASCO Post curated by Contributing Editor George Lundberg, MD, who notes: 

Recent clinical trial results show that immunotherapy—a type of treatment that boosts the immune system to fight cancer—provided long-lasting, improved outcomes for patients with advanced cervical or endometrial cancer. These are important findings for difficult-to-treat cancers.

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Malignant Melanoma Treatment & Management Bookmark

Overview from Medscape curated by Contributing Editor George Lundberg, MD, who notes:

The dramatic array of treatment options now available for this serious disease is nicely summarized in this review. (Free registration required, written with a physician audience in mind.)

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Cervical Cancer—An Overview Bookmark

Overview from Medscape curated by Contributing Editor George Lundberg, MD.

Cervical cancer can be detected early, but when it is fully developed it requires advanced treatment approaches. This comprehensive review outlines treatment options. (Free registration required, written with a physician audience in mind.)

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Molecular Profiling in Metastatic Colorectal Cancer Bookmark

Article from the academic journal Oncology, curated by Contributing Editor George Lundberg, MD, who notes:

Molecular testing is essential to guide effective treatment in metastatic colorectal cancer. This academic review article provides a good overview of the topic.

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