Esophageal Cancer

Article from GenomeWeb curated by Editor in Chief George Lundberg, MD, who notes: 

The U.S. Food and Drug Administration (FDA) has approved the drug pembrolizumab (brand name Keytruda) for solid tumors based solely on whether they have a high tumor mutational burden—a high number of changes in the DNA of the cancer cells.

Go to full article published by GenomeWeb.

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Article from the National Cancer Institute curated by Editor in Chief George Lundberg, MD, who notes: 

In 2019, the U.S. Food and Drug Administration (FDA) approved pembrolizumab for certain advanced esophageal cancers, depending on testing results. The National Cancer Institute explains here.

Go to full article published by the National Cancer Institute.

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Curated by Editor in Chief George Lundberg, MD, who notes:

Esophageal carcinoma is the ninth most frequently diagnosed potentially lethal cancer worldwide, although there is great geographic variation in disease frequency and cell type of origin. This August 2019 treatise from Medscape illustrates all major aspects.

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Article from Cancer Network curated by Editor in Chief George Lundberg, MD, who notes: 

Early diagnosis remains a key for therapeutic success in gastrointestinal (GI) cancers. The sensitivity and specificity of these blood tests are encouraging.

Go to full article published by Cancer Network.

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Research paper from Annals of Surgery curated by Editor in Chief George Lundberg, MD, who notes: 

This meta-analysis found that minimally invasive surgery tops open esophagectomy for esophageal cancer.

Go to full paper published in Annals of Surgery.

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Research paper from The Lancet curated by Editor in Chief George Lundberg, MD, who notes: 

In this clinical trial, nivolumab was somewhat superior to chemotherapy for advanced esophageal carcinoma.

Go to full paper published in The Lancet.

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Article from MedPage Today curated by Editor in Chief George Lundberg, MD, who notes: 

Minimally invasive surgery for esophageal cancer produces similar outcomes with fewer complications than open surgery. A reduction in pulmonary atelectasis may underlie these findings.

Go to full article published by MedPage Today.

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Curated by Editor in Chief George Lundberg, MD, who notes:

Esophageal cancer is common and difficult to treat; causation, classification and diagnosis are evolving. Read here a patient-friendly overview of the disease from the U.S. National Cancer Institute.

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Excerpt:

“ASCO and Friends of Cancer Research (Friends) have submitted recommended language to the U.S. Food and Drug Administration (FDA) for five guidance documents on ways to broaden eligibility criteria for cancer clinical trials. The recommendations are part of an ASCO and Friends collaboration to broaden eligibility for participating in clinical trials by addressing five specific areas: minimum age requirements for trial enrollment, HIV/AIDS status, brain metastases, organ dysfunction, and prior and concurrent malignancies.”

Go to full article published by The ASCO Post on Aug 9, 2018.

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Article from Medscape curated by Editor in Chief George Lundberg, MD, who notes: 

Depression is, for obvious reasons, common in patients with advanced cancer. The old, inexpensive drug ketamine—already approved for medical use by the U.S. Food and Drug Administration (FDA)—seems rapidly effective, according to small studies.

Go to full article published by Medscape.

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Article from ASCO Daily News curated by Director of Scientific and Clinical Affairs, Lola Rahib, PhD.

In collaboration with MD Anderson Cancer Center and the Pancreatic Cancer Action Network, Cancer Commons presented new research at the American Society of Clinical Oncology (ASCO)’s virtual 2020 meeting. The findings show that, by 2040, we will likely see notable changes in which cancer types are most common and which are most deadly, highlighting the influence of cancer screening programs. This research was led by Dr. Rahib at Cancer Commons.

Go to full article published by ASCO Daily News.

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Article from The ASCO Post curated by Editor in Chief George Lundberg, MD, who notes: 

Go to full article published by The ASCO Post.

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Article from The Philadelphia Inquirer curated by Editor in Chief George Lundberg, MD, who notes: 

A new Pennsylvania law requires insurance coverage for use of FDA-approved best drugs first, rather than only after failing with a cheaper alternative.

Go to full article published by The Philadelphia Inquirer.

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Research paper from Nature curated by Editor in Chief George Lundberg, MD, who notes: 

A massive study of thousands of cancers that explores the genomic basis for cancer is being reported simultaneously in dozens of journals. Nature has published this summary article.

Go to full paper published in Nature.

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Article from GenomeWeb curated by Editor in Chief George Lundberg, MD, who notes: 

During the COVID-19 pandemic, some clinical trials have gone virtual.

Go to full article published by GenomeWeb.

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Excerpt from a National Geographic article:

“For now, the sole intervention for vulnerable cancer patients is social distancing and enhanced hygiene practices for their family and health care workers.”

Go to full article published by National Geographic.

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Article from the American Society of Clinical Oncology curated by Editor in Chief George Lundberg, MD, who notes: 

For now, the only definite preventive measures vulnerable patients with cancer can use for themselves and their families are scrupulous social distancing and enhanced personal hygiene; i.e., wash your hands. For more details, ASCO is an authoritative source:

Go to full article published by the American Society of Clinical Oncology.

If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.