liquid biopsy

Advances in Colorectal Cancer Research Bookmark

This outline from the National Cancer Institute covers recent research on colorectal cancer.

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FDA OKs Liquid Biopsy to Identify EGFR-Positive Lung Cancer Bookmark

Article from MedPage Today curated by Editor in Chief George Lundberg, MD, who notes: 

The U.S. Food and Drug Administration (FDA) has approved a liquid biopsy test (a type of biopsy that uses a blood draw instead of surgery) for detecting whether patients have EGFR mutations in their metastatic lung tumors, which could help guide treatment options.

Go to full article published by MedPage Today.

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Brain Tumor Liquid Biopsy Detects DNA Methylation Profiles Bookmark

Article from Clinical OMICs curated by Editor in Chief George Lundberg, MD, who notes: 

Researchers have recently demonstrated a noninvasive way to diagnose and classify brain tumors using a blood test. This promising “liquid biopsy” method detects cell-free tumor DNA in the blood and analyzes its chemical features—specifically, its “methylation patterns”—with high sensitivity and accuracy. Such a test could help guide treatment decisions.

Go to full article published by Clinical OMICs.

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Predicting Prognosis in Glioblastoma Bookmark

Article from The Pathologist curated by Editor in Chief George Lundberg, MD, who notes: 

Liquid biopsy shows surprising apparent prognostic value in glioblastoma multiforme (GBM).

Go to full article published by The Pathologist.

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Liquid Biopsy to Determine Patient Response to Immune Checkpoint Blockade Bookmark

Article from The ASCO Post curated by Editor in Chief George Lundberg, MD, who notes: 

Liquid Biopsy Shows Promise for Monitoring Childhood Brain Tumors Bookmark

Excerpt:

“New research by investigators at the University of California, San Francisco and the Children’s National Health System, has provided early evidence that liquid biopsy testing could help doctors monitor how well treatments are working in kids with diffuse midline gliomas.

“Brain cancers present a challenge for longitudinal monitoring, because obtaining repeat biopsy samples is dangerous and difficult. But liquid biopsy techniques have now opened the possibility of tracking these and other tumors over time based on analysis of tumor genetic material that is shed into the blood or other body fluids.”

Go to full article published by GenomeWeb on Oct 15, 2018.

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Liquid Biopsy IDs More NSCLC Mutations, Yields Patient Therapy Response in Study of Guardant Test Bookmark

Excerpt:

“New data this week has added evidence for the value of blood-based cancer testing in non-small cell lung cancer, demonstrating in a cohort of about 300 that comprehensive liquid biopsy — in this case Guardant Health’s Guardant360 test — can help identify targeted mutations in more patients than tissue sequencing.

“The study also found that patients treated on the basis of blood-based test results respond to treatment similarly to those treated based on tissue test results.”

Go to full article published by GenomeWeb on Oct 12, 2018.

If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.