August 9, 2019
Neuroendocrine Neoplasms of the Pancreas BookmarkGeorge Lundberg, MD
Curated by Editor in Chief George Lundberg, MD:
The pancreas is made up of three main cellular components: glands, ducts, and hormone-producing cells, some of which are known as neuroendocrine cells. All can develop malignant tumors, with very different characteristics.
To learn more about pancreatic neuroendocrine tumors, which begin in neuroendocrine cells in the pancreas, check out this comprehensive, authoritative, detailed, up-to-date, unbiased overview from Medscape. (Free registration may be required to view the content.)
March 11, 2016
New Treatments for Gastrointestinal Neuroendocrine TumorsEmma Shtivelman, PhD
Neuroendocrine tumors (NETs) of the digestive system (GI-NETs) can arise in different parts of the digestive tract…Two new treatments for GI-NETs recently received much attention at the 2016 Gastrointestinal Cancers Symposium held in San Francisco in January. Researchers at the symposium presented clinical trial results that demonstrated the benefits of these new drugs.
July 12, 2015
Hormone-Mimicking Drugs Are Used To Treat Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)Emma Shtivelman, PhD
Neuroendocrine tumors (NETs) can arise wherever neuroendocrine (hormone-producing) cells are found—which is in most organs. Most NETs (65%-70%) are gastroenteropancreatic, or GEP, arising in different gastrointestinal organs. GEP-NETs are most commonly found in the small bowel (including the appendix), stomach, and rectum. Still, NETs in general are rare, which complicates the development of new treatments and identification of the genetic drivers of these cancers. Treatment of GEP-NETs is clearly an unmet medical need, and is now even more urgent because their incidence has been on the rise in the last 20 years.