PD-L1-positive
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August 15, 2020
Key Studies in Metastatic Breast Cancer From ASCO 2020 Bookmark
George Lundberg, MDArticle from Medscape curated by Editor in Chief George Lundberg, MD, who notes:
This year’s virtual meeting of the American Society of Clinical Oncology (ASCO) featured five important studies on metastatic breast cancer, as outlined in this video.
Go to full article and video published by Medscape.
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April 8, 2019
Atezolizumab/Nab-Paclitaxel Approved by the FDA for PD-L1+ TNBC Bookmark
Emma Shtivelman, PhDExcerpt:
“An accelerated approval has been granted by the FDA for the combination of atezolizumab (Tecentriq) and nab-paclitaxel (Abraxane) as a frontline treatment for patients with unresectable locally advanced or metastatic PD-L1–positive triple-negative breast cancer (TNBC).
“The approval is based on the phase III IMpassion130 trial, in which the addition of the PD-L1 inhibitor atezolizumab to nab-paclitaxel reduced the risk of progression or death by 40% compared with nab-paclitaxel alone in this patient population.”
Go to full article published by Targeted Oncology on March 8, 2019.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.
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October 1, 2018
Pembrolizumab Alone or With Chemotherapy for PD-L1–Positive NSCLC? Bookmark
Emma Shtivelman, PhDExcerpt from Cancer Network:
“Researchers found that in patients with non–small-cell lung cancer (NSCLC) and a Tumor Proportion Score (TPS) ≥ 50, pembrolizumab plus chemotherapy failed to improve overall survival (OS) or progression-free survival (PFS) compared with pembrolizumab alone.
“Results from the study were presented in a poster presentation at the International Association for the Study of Lung Cancer (IASLC) 19th World Conference on Lung Cancer, held September 23–26 in Toronto.”
Go to full article published by Cancer Network on Sep 24, 2018.
If you’re wondering whether this story applies to your own cancer case or a loved one’s, we invite you to get support from Cancer Commons.