personalized medicine

  • August 18, 2023  

    Alibrex: A New Blood Test to Reveal Whether a Cancer Treatment is Working

    With: Kevin Knopf, MD, MPH

    In cancer treatment, time is of the essence. Our Curious Dr. George asks Kevin B. Knopf, MD, MPH, Chief Medical Officer at Cadex Genomics, how his company’s new test, Alibrex, could rapidly reveal how well a given treatment is working for a given patient. Curious Dr. George: The U.S. Food and Drug Administration has approved about 270 anti-cancer drugs. The National Comprehensive Cancer Network… Read more »

  • August 11, 2023  

    Common Sense Oncology: Moving Back Towards Outcomes that Matter

    With: Christopher M. Booth, MD, FRCPC

    There are many ways to measure how well a particular cancer treatment works. But how much do these outcomes reflect a patient’s actual wellbeing? Our Curious Dr. George asks Christopher M. Booth, MD, FRCPC, one of the founding leaders of the new international initiative “Common Sense Oncology” (CSO), how CSO is working to improve patient outcomes. Curious Dr. George: The practice of clinical oncology… Read more »

  • June 30, 2023  

    PARIS Test Uses Lab-Grown Mini-Tumors to Find a Patient’s Best Treatment

    With: Carla Grandori, MD, PhD

    The U.S. Food and Drug Administration (FDA) has approved hundreds of drugs for the treatment of cancer. However, some approved drugs are more effective for certain patients than others. Our curious Dr. George asks Carla Grandori, MD, PhD, Founder and CEO of SEngine Precision Medicine, about her company’s test to detect which drugs are likely to be most effective for a given patient’s solid tumor.… Read more »

  • March 16, 2023  

    A New Biomarker to Optimize Immunotherapy for People with Cancer

    With: Scott Tomlins, MD, PhD

    Immunotherapy—a type of treatment that harnesses a patient’s own immune system to fight cancer—has been a “game changer” for many patients. It can be difficult, however, to predict whether or not a given person would benefit from immunotherapy, especially when it comes to drugs that target the immune system molecules PD-1 and PD-L1. Our Curious Dr. George asks Scott Tomlins, MD, PhD, Co-founder and… Read more »

  • March 7, 2023  

    Learnings from Pilot Study: Creating Treatment Templates to Serve More Glioblastoma Patients

    With: Adrienne Nugent, PhD

    A recent pilot study between Cancer Commons and the Musella Foundation for Brain Tumor Research & Information is identifying patterns that are being translated into treatment templates to better serve a larger group of GBM patients. Our Curious Dr. George asks Cancer Commons Scientist Adrienne Nugent, PhD, to discuss key factors that point to the best courses of action a patient might take, and about the clinical… Read more »

  • January 28, 2023  

    Using Live Cells from Patients to Find the Right Cancer Drug

    With: Clifford A. Reid, PhD

    Today, many cancer patients benefit from targeted drugs that are matched to the distinct genetic mutations found in their tumors. However, especially in late-stage cancer, this “precision oncology” strategy has not proven to be as transformative as people once hoped. Here, Curious Dr. George asks Clifford A. Reid, PhD, CEO of Travera, how his company is addressing this problem. Curious Dr. George: The U.S.… Read more »

  • August 23, 2022  

    Using AI and Drug Testing to Design Personalized Cancer Drug Combos

    With: Noah Berlow, PhDDiana Azzam, PhD

    Advanced cancer treatment often involves combining multiple drugs. But with a huge number of possible combinations, it is difficult to know which mix might work best for each patient. Here, our Curious Dr. George asks two leaders to describe how the company First Ascent Biomedical is addressing this challenge. Curious Dr. George: The U.S. Food and Drug Administration (FDA) has approved many thousands of… Read more »

  • July 8, 2022  
  • July 1, 2022  
  • June 10, 2022  

    NCI Overview of Uterine Cancer Bookmark

    George Lundberg, MD

    The National Cancer Institute provides this online overview of uterine cancer that is up-to date, comprehensive, and written specifically for patients.

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